Connect with SPT Labtech at SLAS 2025
17/12/2024
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17/12/2024
This January, SLAS 2025 headed to San Diego! This year's theme, Curiosity Igniting Innovation, was all about the drive to push boundaries and make a difference.
We joined other industry leaders, to explore how the latest in lab automation is helping scientists around the world achieve breakthroughs that truly make a difference to human health. In case you missed out on any of our precision liquid handling and robust sample management technology, user success stories or educational resources, you can find out more below.
Our latest innovation in genomics liquid handling firefly+ was on display. firefly+ builds on the foundations of our all-in-one platform with an integrated thermocycler and additional labware capacity, all while maintaining our commitment to usability and compact design. With firefly+, you can run fully automated NGS library preparation workflows, maximizing walkaway time and giving your team more time to focus on what's important.
comPACT made its debut on the road! If you’re ready to leave behind the hassle of manually sample storage and retrieval, and want to protect your valuable research and data, comPACT is here to help. Our powerful, yet user-friendly solution offers flexible, secure tube storage in a smaller footprint, bringing the benefits of automated sample management to even more labs. Built with our proven pneumatic technology and modular design, comPACT lets you start small and scale up as your needs grow, ensuring your samples remain stable and easily accessible every step of the way.
Automated screening in academia: How are leading research institutes addressing the urgent need for novel TB therapies? In our tutorial led by Peter Craggs, Pharmacology Expert at The Francis Crick Institute, we learned how a multi-partner collaboration is building on previous GSK efforts to identify and validate new targets against an under-explored area in TB drug discovery.
In this work, a high-throughput repurposing screening approach has been taken to identify inhibitors from a library of 6,000 existing compounds. This project was enabled by building an integrated automated workflow in collaboration with SPT Labtech and Automata. The non-contact positive displacement dispenser, dragonfly® discovery from SPT Labtech, delivered fast and precise liquid handling, while the Automata LINQ platform allowed seamless end-to-end assay automation of such a time-sensitive kinetic assay. This collaborative, integrated approach accelerated the discovery of novel Mtb enzyme inhibitors and laid the groundwork for further medicinal chemistry efforts to develop this promising class of antitubercular agents.
Our technology has been successfully implemented in laboratories around the world - Check out some of the posters we had on display at SLAS this year which showcase these research findings!
Mon 27 Jan - 12-1pm PST - Poster 1380-A
We demonstrate that the Roche KAPA EvoPlus V2 and KAPA EvoPlus V2 PCR-free DNA library preparation workflows can be successfully automated on firefly to create Illumina-compatible NGS libraries comparable to those prepared manually. The combination of these technologies enables significant time savings in the laboratory for whole genome sequencing applications, whilst also reducing operator variability.
Mon 27 Jan - 2-3pm PST - Poster 1385-B
Using dedicated software and automation, Artios have developed in-house compound management for Design-Make-Test-Analyze processing and assay-ready plate generation. This results in:
- Increased sample and data integrity through audited and trackable processes
- Reduced cycle times and cost
- Faster data reporting for better decision making and use of resources
Tue 28 Jan - 12-1pm PST - Poster 1386-C
This poster highlights how mosquito HV genomics has been used to automate the Illumina Nextera XT protocol at SEQ-IT, achieving 5X miniaturized reaction volumes while delivering reproducible, high-quality libraries. This miniaturized method was developed to identify and screen mutations with oncogenic potential and drug resistance (HIV, HBV, HCV), SNP detection, as well as in HLA-typing, among other applications.
Mon 27 Jan - 12-1pm PST - Poster 1212-A
The ICESTP Safety Panel 90 includes 138 assays, incorporating both single-point screening and dose-response screening with a functional assay format, such as Automatic patch clamp, FLIPR calcium flow, and HTRF, for example. In this poster, we demonstrate the use of firefly® for high-throughput sample processing to facilitate the safety assessment of a 90-target panel, to improve the efficiency and accuracy of drug safety evaluations.
Mon 27 Jan - 12-1pm PST - Poster 1252-A
The DToL initiative aims to advance our understanding of life on Earth by unravelling the genetic blueprintt of a wide range of organisms. To address the scale of this challenge, the team at the WSI describe the development and validation of a novel automated method on firefly® to construct whole genome sequencing libraries from genomic DNA using the PacBio SMRTbell prep kit 3.0.
Tue 28 Jan - 2-3pm PST - Poster 1383-D
Cellular agriculture could be instrumental to environmentally-friendly food production. However, high raw materials costs impede financial viability. This poster highlights how the team at Uncommon have applied automated liquid handling and Design of Experiment (DoE) methodology to drive the development of low-cost, animal-free media.
Mon 27 Jan - 2-3pm PST - Poster 1389-B
In this study, we explore the benefits of automating the Scale Bio single cell methylation protocol with SPT Labtech’s firefly® to facilitate the analysis of single cell methylomes isolated from human peripheral blood mononuclear cells (PBMCs) compared to a library prepared in parallel using manual methods.
Mon 27 Jan - 12-1pm PST - Poster 1388-A
We demonstrate the ease of automating NEB’s UltraExpress® kits with the user-friendly firefly system, achieving high-quality and reproducible libraries and sequencing data. Libraries were prepared from 25 ng to 250 ng of total RNA, consistently showing high data quality across this input range.
Mon 27 Jan - 2-3pm PST - Poster 1089-B
EditCo's automated NGS library preparation workcell and software are built to handle a huge array of CRISPR edits reliably every time within unique constraints. Learn how the team automated oligo inventory management with comPOUND to minimize manual intervention and save valuable time.
Our team of experts are always on hand to answer any questions or arrange a demo of our solutions if you'd like to see them for yourself - so get in touch if you'd like to learn more!
